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Dr. Heather Eisler
Assistant Professor of Biology

A. Hockert

Dr. Heather Eisler graduated from the University of Northern Colorado with a BA in Chemistry and Biology in 1999.  She also became licensed to teach elementary education in Colorado.   Dr. Eisler moved across the Rockies to study Molecular Biology at Utah State University, where she earned an MS in 2002.  Her studies in Genomics, Speciation, and hybrid sterility continued at the University of Notre Dame in Indiana, where she earned her Ph.D. in 2009.  While at Notre Dame, Dr. Eisler was recognized for teaching with both a Certificate of Teaching Excellence and an Outstanding Graduate Student Teacher Award.  Her research was supported by an NSF: Doctoral Dissertation Improvement Grant.  Before coming to the University of the Cumberlands, Dr. Eisler taught Biotechnology at St. Mary’s College.

Dr. Eisler continues to be fascinated by differences in genes between species.  She is currently working with students to annotate portions of the fourth chromosome of several species of Drosophila.  The fourth chromosome is of particular interest, as it harbors large portions of heterochromatin and few expressed genes.  Since the heterochromatin does not undergo meiotic recombination, these are regions that are frequently quite different between species.  Interestingly, this chromosome is the most like our human chromosomes.

Courses taught

  • BIOL 110 – General Biology Laboratory
  • BIOL 131 – General Biology
  • BIOL 113 – Population Biology Laboratory
  • BIOL 345 – Microbiology
  • BIOL 495 – Senior Seminar

Presentations and Publications

Eisler, HL., Romero-Severson, J., and Hollocher H.  When Genomes collide: Examination of
expression profile differences underlying female hybrid sterility in Drosophila. In
preparation.

Eisler, HL., Gloss, A.**, Lobo, NF., Hollocher H. Hmrand Lhrexpression in D. simulans/D.
melanogasterhybrid females and their relation to variable oogenic development.  In preparation.

** Notre Dame undergraduate

Eisler, HL.,Richardville, K.^, Hollocher, H. What makes a mate attractive?  Mate choice and
genomic examination of courtship gene expression in female D. simulans/D. melanogaster hybrids. In preparation for Behavioral Genetics.

^ High school teacher

Eisler, HL., Lobo, NF., Hollocher, H. Examination of expression differences in different splice
variants of out at first (oaf) in D. simulans/D. melanogaster hybrid females in relation to variable oogenicdevelopmenyt.  In preparation.

Eisler, H., Romero-Severson, J., and Hollocher H. Not just a boys club anymore: The role of
Hmr and Lhr in the fertility rescue of D. simulans/D. melanogaster hybrid females. 
Presented at the Annual Meeting of the Society for the Study of Evolution. June 2008:
Minneapolis. MN.

Gloss, A.*, Eisler, H., Lobo, N., and Hollocher, H. Effects of gene expression differences on hybrid fertility in Drosophila simulans/melanogaster crosses.University of Notre Dame’s College of Science-Joint Annual Meeting. May 2008: Notre Dame, IN.

Keating, E.*, Eisler, H., and Hollocher, H.Fertility in Drosophila simulans, D. mauritiana,
and D. sechellia hybrids.University of Notre Dame’s College of Science-Joint Annual Meeting. May 2008: Notre Dame, IN.

* presented by a Notre Dame undergraduate

Eisler, H., Romero-Severson, J., and Hollocher H. Mom vs Dad: Who is better for a female hybrid to express her genes like? Presented at the Annual Meeting of the Society for Molecular Biology and Evolution. June 2007: Halifax, NS, Canada.

Eisler, H., Romero-Severson, J., and Hollocher H. When Genomes Collide: Additivity, dominance, and female fertility of D. simulans/D. melanogaster hybrids. Presented at the Annual Meeting of the Society for the Study of Evolution. June 2006: Stony Brook, NY.

Eisler, H., Romero-Severson, J., and Hollocher H.A genome-wide examination of D. simulans/D. melanogaster female hybrid sterility.Presented at the Annual Meeting of the Society for the Study of Evolution. June 2005: Fairbank, AK.