In this course, students receive instruction in research methods and application in the clinical setting. They integrate basic concepts of epidemiology and statistics as these concepts relate to medical practice. Students critically read published reports of clinical research and identify strengths and weaknesses in the structure and presentation of data and conclusions in those reports. They interpret and search evidence-based literature related to clinical problems encountered in physician assistant practice. Students will choose a proposal topic that will then be developed during the clinical year in the Capstone I course. Students will be given the opportunity to select from a menu of possibilities. This includes the following: Quasi-experimental study with data gathering and analysis, case based study, evidence-based medicine project with comprehensive literature review, and community-based research.